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How can I uninstall applications that are locked by phone vendor?
Is there an easy way to remove pre-installed apps on my HTC Droid Incredible?
Are there risks involved in removing them, such as a voided warranty?
You can only fully uninstall pre-installed applications by using ADB. You need to find out what the package name is for the specific app, and enter this in the ADB prompt:
adb uninstall <package.name>
For example, to remove the Maps application:
adb uninstall com.google.android.apps.maps
So far I haven't found an easy way to figure out the package name for an app though.